Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21473769 | 0.84 | CYP1A2 (0.38) | CYP2A6ALDH1A1CYP1A2KDM4ELMNA | |
| SCHEMBL19774426 | 0.84 | ALDH1A1 (0.36) | CYP2A6ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL179171 | 0.83 | ALDH1A1 (0.48) | CYP2A6ALDH1A1ITKGRM2KDM4E | |
| SCHEMBL21475592 | 0.82 | CYP1A2 (0.35) | CYP2A6ALDH1A1CYP1A2KDM4ELMNA | |
| SCHEMBL12950335 | 0.80 | — | — | |
| SCHEMBL179186 | 0.80 | ALDH1A1 (0.37) | CYP2A6ALDH1A1ITKGRM2KDM4E | |
| SCHEMBL24699292 | 0.79 | CYP1A2 (0.38) | CYP2A6ALDH1A1CYP1A2KDM4ELMNA | |
| SCHEMBL179244 | 0.79 | CYP2A6 (0.34) | CYP2A6ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL21511939 | 0.79 | ALDH1A1 (0.35) | CYP2A6ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL10069238 | 0.79 | PTGDR2 (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11512039-B2 | Aromatic amine derivatives, preparation methods therefor, and uses thereof | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2022-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11512039-B2 | Aromatic amine derivatives, preparation methods therefor, and uses thereof | SLC7A1, WEE1, SLC7A5 | CYP2A6 2010/4885ALDH1A1 278/4885ITK 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.