Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 6/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30016058 | 1.00 | MTOR (0.36) | MTORMAPK1HSD17B10USP2S1PR1 | |
| SCHEMBL24699210 | 0.93 | MTOR (0.35) | MTORMAPK1HSD17B10USP2S1PR1 | |
| SCHEMBL30015825 | 0.93 | MTOR (0.35) | MTORMAPK1HSD17B10USP2S1PR1 | |
| SCHEMBL30016531 | 0.92 | PI4KB (0.36) | MTORMAPK1HSD17B10USP2S1PR1 | |
| SCHEMBL24697976 | 0.92 | PI4KB (0.36) | MTORMAPK1HSD17B10USP2S1PR1 | |
| SCHEMBL24699243 | 0.90 | KDM1A (0.33) | MTORMAPK1HSD17B10USP2S1PR1 | |
| SCHEMBL30015914 | 0.86 | MAPK1 (0.41) | MTORMAPK1HSD17B10USP2S1PR1 | |
| SCHEMBL24699495 | 0.86 | MAPK1 (0.41) | MTORMAPK1HSD17B10USP2S1PR1 | |
| SCHEMBL24699069 | 0.85 | PI4KB (0.35) | MTORMAPK1HSD17B10USP2S1PR1 | |
| SCHEMBL30015941 | 0.85 | PI4KB (0.35) | MTORMAPK1HSD17B10USP2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |