Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12136890 | 1.00 | KDM4E (0.33) | KDM4EMAPTMAPK1CCKBR | |
| SCHEMBL246997 | 0.74 | MAPT (0.44) | KDM4EMAPTMAPK1CCKBR | |
| SCHEMBL3500609 | 0.68 | CCKBR (0.38) | KDM4EMAPTMAPK1CCKBR | |
| SCHEMBL1354792 | 0.67 | PLK4 (0.34) | — | |
| SCHEMBL1354791 | 0.67 | PLK4 (0.34) | — | |
| SCHEMBL24427686 | 0.67 | KDM1A (0.35) | — | |
| SCHEMBL12136883 | 0.67 | MAPT (0.33) | KDM4EMAPTMAPK1 | |
| SCHEMBL19000170 | 0.67 | MAPT (0.33) | KDM4EMAPTMAPK1 | |
| SCHEMBL1354280 | 0.67 | MAPT (0.33) | KDM4EMAPTMAPK1 | |
| SCHEMBL20428806 | 0.66 | MAPT (0.40) | KDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216973-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-22 | — | — | US | disclosed |
| US-8859592-B2 | Insecticidal compounds | SYNGENTA CORP PROTECTION LLC (US) | 2014-10-14 | — | — | US | disclosed |
| US-20130245072-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CORP PROTECTION LLC (US) | 2013-09-19 | — | — | US | disclosed |
| EP-2331536-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-08-21 | — | — | EP | disclosed |
| US-20130165485-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-27 | — | — | US | disclosed |
| US-20110288089-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-03 | — | — | US | disclosed |
| EP-2331536-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010020522-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288089-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | KDM4E 3205/4885MAPT 3636/4885MAPK1 1487/4885 |
| US-20130165485-A1 | INSECTICIDAL COMPOUNDS | CHRM1, CHRM2, CHRM5 | KDM4E 2816/4885MAPT 3793/4885MAPK1 1036/4885 |
| US-20130245072-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | KDM4E 3205/4885MAPT 3636/4885MAPK1 1487/4885 |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | CHRM1, CHRM2, C1R | KDM4E 2708/4885MAPT 4058/4885MAPK1 1117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.