Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20382858 | 0.84 | ACHE (0.33) | — | |
| SCHEMBL607938 | 0.80 | — | — | |
| SCHEMBL610169 | 0.75 | — | — | |
| SCHEMBL19566767 | 0.69 | MAPT (0.42) | ALDH1A1TP53TSHR | |
| SCHEMBL24092972 | 0.66 | — | — | |
| SCHEMBL24092978 | 0.65 | — | — | |
| SCHEMBL24611191 | 0.65 | HRH3 (0.37) | ALDH1A1 | |
| SCHEMBL9445053 | 0.65 | ACHE (0.37) | ALDH1A1TSHR | |
| SCHEMBL214239 | 0.65 | ACHE (0.37) | ALDH1A1TSHR | |
| SCHEMBL609158 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022195287-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TREM2 | BICYCLETX LIMITED (GB) | 2022-09-22 | — | — | WO | disclosed |