Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102484 | 0.76 | GSTP1 (0.37) | GSTP1 | |
| SCHEMBL3603099 | 0.70 | GSTP1 (0.38) | GSTP1 | |
| SCHEMBL11104225 | 0.66 | PTPRC (0.38) | GSTP1 | |
| SCHEMBL11336110 | 0.66 | GSTP1 (0.36) | GSTP1 | |
| SCHEMBL16714050 | 0.65 | GSTP1 (0.41) | GSTP1 | |
| SCHEMBL1804084 | 0.64 | — | — | |
| SCHEMBL616033 | 0.61 | GSTP1 (0.42) | GSTP1 | |
| SCHEMBL26987773 | 0.61 | TP53 (0.39) | GSTP1 | |
| SCHEMBL5664113 | 0.61 | CYP3A4 (0.56) | — | |
| SCHEMBL11052840 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596074-B1 | HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF CYSTIC FIBROSIS | FONDAZIONE ST ITALIANO TECNOLOGIA (IT) | 2022-12-14 | — | — | EP | disclosed |