⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19011768 | 0.72 | PIK3CD (0.35) | — | |
| Hydrochloric Acid SCHEMBL27920596 | 0.69 | — | — | |
| SCHEMBL731563 | 0.65 | — | — | |
| SCHEMBL3814365 | 0.65 | ACHE (0.38) | — | |
| SCHEMBL2851896 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL21640973 | 0.63 | — | — | |
| SCHEMBL27927653 | 0.61 | — | — | |
| SCHEMBL12695000 | 0.61 | — | — | |
| SCHEMBL7087475 | 0.61 | — | — | |
| SCHEMBL27006697 | 0.60 | CHRM1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746100-B2 | Cycloalkyl pyrimidines as ferroportin inhibitors | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| US-20230226074-A1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2023-07-20 | — | — | US | disclosed |
| US-20220396562-A1 | CYCLOALKYL PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. | 2022-12-15 | — | — | US | disclosed |