⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21754752 | 0.84 | CHRM5 (0.34) | — | |
| SCHEMBL16210110 | 0.65 | SOD3 (0.33) | — | |
| SCHEMBL38653487 | 0.64 | CREBBP (0.36) | — | |
| SCHEMBL19110594 | 0.64 | KDM4E (0.38) | — | |
| SCHEMBL31699363 | 0.63 | ADORA1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL19097314 | 0.60 | TSHR (0.37) | — | |
| SCHEMBL22813237 | 0.60 | — | — | |
| SCHEMBL18798821 | 0.60 | CHRM5 (0.36) | — | |
| SCHEMBL17229801 | 0.60 | CHRM3 (0.47) | — | |
| SCHEMBL21754754 | 0.59 | CHRM5 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220387400-A1 | FORMULATIONS OF RBP4 INHIBITORS AND METHODS OF USE | Belite Bio (HK) Limited (HK) | 2022-12-08 | — | — | US | disclosed |