SOD3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Hydrochloric Acid (SCHEMBL9050381)	0.55	2/20
Hydrochloric Acid (SCHEMBL27481262)	0.55	2/20
Hydrochloric Acid (SCHEMBL27496406)	0.55	2/20
SCHEMBL162842	0.54	2/20
SCHEMBL744493	0.54	2/20
SCHEMBL744931	0.54	2/20
SCHEMBL745010	0.54	2/20
SCHEMBL2581399	0.54	2/20
SCHEMBL2762041	0.54	2/20
SCHEMBL3716714	0.54	2/20
SCHEMBL5394694	0.54	2/20
SCHEMBL7336599	0.54	2/20
SCHEMBL8723279	0.54	2/20
SCHEMBL10379383	0.54	2/20
SCHEMBL11749102	0.54	2/20
SCHEMBL21581257	0.54	2/20
SCHEMBL21581259	0.54	2/20
SCHEMBL21581269	0.54	2/20
SCHEMBL21581281	0.54	2/20
SCHEMBL21581298	0.54	2/20

Clinical trials — most relevant to SOD3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Adding Dexmedetomidine to Bupivacaine for Bilateral Erector Spinae Block	PHASE4	UNKNOWN
The Potential Hepatoprotective Effect of Metformin in Patients With Beta Thalassemia Major	PHASE4	UNKNOWN
Randomized Controlled Trial of Silymarin in Asthma	PHASE2/PHASE3	WITHDRAWN
Cardioprotective Effects of Melatonin in Patients With Cardiomyopathy	PHASE3	RECRUITING
Ozone-based Eye Drops as Adjuvant Therapy in Microbial Keratitis	PHASE3	UNKNOWN
SOD1 Inhibition by Pyrimethamine in Familial Amyotrophic Lateral Sclerosis (ALS)	PHASE1/PHASE2	COMPLETED
Safety Study of High Doses of Zinc in ALS Patients	PHASE1/PHASE2	COMPLETED
Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy	PHASE2	RECRUITING
Beneficial Effect of Silymarin in Ulcerative Colitis	PHASE2	RECRUITING
Efficacy and Safety of Black Seed Oil With Vonoprazan Based Triple Therapy in Treatment of Helicobacter Pylori	PHASE2	ACTIVE_NOT_RECRUITING
Efficacy and Safety of Oral Immunotherapy With GcMAF in Hospitalized Patients With COVID-19 Pneumonia	PHASE2	COMPLETED
A Supervised Nutritional Program in Pregnancies and NF-κB Expression in Placenta	PHASE1	COMPLETED
The Impact of Zinc Supplementation on Left Ventricular Function in Nonischemic Cardiomyopathy	PHASE1	COMPLETED
[18F]ACI-19626 PET in TDP-43 Proteinopathies	EARLY_PHASE1	RECRUITING
ADAPT: Efficacy of a Dietary Supplement During and After Exercise	nan	COMPLETED
A Case Control Study of Resveratrol Effects in Coronary Artery Disease Patients With Metabolic Syndrome	nan	COMPLETED
Efficacy of Superoxide Dismutase in Preventing Radiation Dermatitis in Patients With Head and Neck Cancer .	nan	WITHDRAWN
Efficacy and Safety of Ovotransferrin in COVID-19 Patients	nan	UNKNOWN
Analysis of Post-Translational Modifications of a Critical Protein Implicated in Amyotrophic Lateral Sclerosis	nan	COMPLETED
Effects of Green Tea Extract (GTE) on Systemic Oxidative and Antioxidative Status in Chinese Patients With Stable Asthma	nan	COMPLETED
Efficacy of Superoxide Dismutase Spray in Preventing Radiation Dermatitis in Patients With Head and Neck Cancer .	nan	WITHDRAWN
Effect of Oral Zinc and Vitamin E Supplementation on Short-term Postoperative Outcomes in Cardiac Surgery Patients.	nan	COMPLETED
Oxidative Stress in Intestinal Metaplasia and Metabolic Syndrome	nan	UNKNOWN
Ginkgo Biloba Extract for Schizophrenia	nan	COMPLETED
The Influence of Melatonin Supplementation in the Group of Persons Performing Competitive Sport.	nan	COMPLETED
Markers of Oxidative Stress in Inflammatory Bowel Diseases: Risk Factors and Implications for a Dietetic Approach	nan	ACTIVE_NOT_RECRUITING
Cardioprotective Effect of Melatonin Versus Vitamin D in Breast Cancer Patients Receiving Doxorubicin	nan	NOT_YET_RECRUITING
Oxidative Stress in Testicular Tissue Before and After Cryopreservation	nan	COMPLETED
Characterization of the Nrf2 Response in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD)	nan	RECRUITING
Pleiotropy and Mechanism of Peripheral Nerve Related Genes in the Progression of Amyotrophic Lateral Sclerosis	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a SOD3 binder may also engage these)

Protein	Name	Similarity
P41975	—	1.000	P41975 →
Q08420	—	0.989	Q08420 →
O09164	—	0.988	O09164 →
Q5XIL0	—	0.976	Q5XIL0 →
Q92791	—	0.975	Q92791 →
Q9CQ04	—	0.975	Q9CQ04 →
Q9VGY6	—	0.975	Q9VGY6 →
B4JTF5	—	0.974	B4JTF5 →
B3LV44	—	0.974	B3LV44 →
B4LZT9	—	0.974	B4LZT9 →
Q2R2W8	—	0.974	Q2R2W8 →
Q9WU47	—	0.974	Q9WU47 →
Q9NXH8	—	0.973	Q9NXH8 →
B4G2I8	—	0.973	B4G2I8 →
Q6JHU8	—	0.973	Q6JHU8 →
Q53JI9	—	0.973	Q53JI9 →
Q8NI99	—	0.973	Q8NI99 →
O35764	—	0.973	O35764 →
Q8N8M0	—	0.973	Q8N8M0 →
Q01634	—	0.973	Q01634 →
Q7FA29	—	0.972	Q7FA29 →
Q90830	—	0.972	Q90830 →
O75064	—	0.972	O75064 →
Q75BD5	—	0.972	Q75BD5 →
Q4KLM6	—	0.972	Q4KLM6 →
Q758T2	—	0.972	Q758T2 →
B4GALT1	Beta-1,4-galactosyltransferase 1	0.972	landscape →
Q9P2W7	—	0.972	Q9P2W7 →
Q6P768	—	0.972	Q6P768 →
O54858	—	0.972	O54858 →