Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.48 |
| ▸ | FDPS | P14324 | 11/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL27976404 | 0.91 | TSHR (0.44) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Phosphoric Acid SCHEMBL27819280 | 0.91 | TSHR (0.44) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Phosphoric Acid SCHEMBL27854661 | 0.91 | TSHR (0.44) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Phosphoric Acid SCHEMBL27488492 | 0.91 | TSHR (0.44) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Phosphoric Acid SCHEMBL27854663 | 0.91 | TSHR (0.44) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Phosphoric Acid SCHEMBL25392228 | 0.91 | TSHR (0.44) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Phosphoric Acid SCHEMBL27607015 | 0.91 | TSHR (0.44) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Phosphoric Acid SCHEMBL2471199 | 0.91 | TSHR (0.44) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Dodecane SCHEMBL8507148 | 0.85 | LPAR3 (0.56) | LPAR3LPAR2FDPSGGPS1LPAR1 | |
| Heptane SCHEMBL27959095 | 0.83 | LPAR3 (0.59) | LPAR3LPAR2FDPSGGPS1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115337242-A | Traditional Chinese medicine composition, extract, preparation method and application thereof, cosmetics and medicines | 新生活化妆品科技(上海)有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-103324069-B | Lubricant supply device, image forming apparatus and handle box | 株式会社理光 | 2016-06-08 | — | — | CN | disclosed |
| CN-103298857-A | Cosmetic containing liquid organopolysiloxane | DOW CORNING TORAY CO LTD | 2013-09-11 | — | — | CN | disclosed |
| CN-102781420-A | Powder-dispersing agent comprising silicone phosphoric acid trimester, surface-coated/treated powder, and cosmetic | KOSE CORP | 2012-11-14 | — | — | CN | disclosed |
| CN-101227889-B | Cosmetics comprising a modified organopolysiloxane | DOW CORNING TORAY CO LTD | 2012-11-07 | — | — | CN | disclosed |
| CN-101415641-B | Modified clay mineral | AJINOMOTO CO.,INC. (JP) | 2012-02-08 | — | — | CN | disclosed |
| CN-102274133-A | Cosmetic product containing film-forming polymer | — | 2011-12-14 | — | — | CN | disclosed |
| CN-102257040-A | Partially hydrocarbon group-blocked (poly) glycerol-modified polysiloxane, method for producing same, and cosmetic composition containing same | DOW CORNING TORAY CO LTD | 2011-11-23 | — | — | CN | disclosed |
| EP-1614411-B1 | OILY MAKEUP COSMETICS | KANEBO COSMETICS INC (JP) | 2011-10-05 | — | — | EP | disclosed |
| CN-102058492-A | Cosmetic | SHINETSU CHEMICAL CO | 2011-05-18 | — | — | CN | disclosed |
| CN-1706797-A | Oily ingredient for cosmetic prepn. and cosmetic prepn. | KYOWA YUKA KK (JP) | 2005-12-14 | — | — | CN | disclosed |
| CN-1197542-C | Cosmetics | KYOWA HAKKO KOGYO KK (JP) | 2005-04-20 | — | — | CN | disclosed |
| CN-1187033-C | Foundation | KAO CORP (JP) | 2005-02-02 | — | — | CN | disclosed |
| CN-1541088-A | Oil for cosmetic and cosmetic | Э���ͻ���ʽ���� | 2004-10-27 | — | — | CN | disclosed |
| CN-1518968-A | Absorbent article | ������������ʽ���� | 2004-08-11 | — | — | CN | disclosed |
| CN-1518967-A | Absorbent article | ������������ʽ���� | 2004-08-11 | — | — | CN | disclosed |
| CN-1470225-A | Absorbent article | 花王株式会社 | 2004-01-28 | — | — | CN | disclosed |
| CN-1328813-A | Cosmetics | KYOWA HAKKO KOGY CO LTD (JP) | 2002-01-02 | — | — | CN | disclosed |
| CN-1185313-A | Powdered cosmetic composition | KAO CORP (JP) | 1998-06-24 | — | — | CN | disclosed |
| CN-1171235-A | Foundation | KAO CORP (JP) | 1998-01-28 | — | — | CN | disclosed |