Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 4/20 | 0.52 |
| ▸ | GPR6 | P46095 | 13/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2468387 | 0.93 | SCD (0.50) | SCDCHRM4 | |
| SCHEMBL2468437 | 0.90 | SCD (0.55) | SCDGPR6 | |
| SCHEMBL2466547 | 0.86 | SCD (0.51) | SCDCHRM4 | |
| SCHEMBL1377539 | 0.85 | SCD (0.71) | SCD | |
| SCHEMBL2469266 | 0.84 | SCD (0.73) | SCD | |
| SCHEMBL2474582 | 0.81 | SCD (0.52) | SCD | |
| SCHEMBL2474664 | 0.80 | SCD (0.54) | SCDCHRM4 | |
| SCHEMBL2469865 | 0.80 | SCD (0.54) | SCDCHRM4 | |
| SCHEMBL2464993 | 0.78 | SCD (0.75) | SCD | |
| SCHEMBL2471109 | 0.78 | SCD (0.74) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648874-B1 | PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2011-10-05 | — | — | EP | claimed |
| EP-1846035-B1 | COMBINATION THERAPY | XENON PHARMACEUTICALS INC (CA) | 2011-09-21 | — | — | EP | claimed |