Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2471779 | 0.86 | DPP4 (0.33) | DPP4DPP7 | |
| SCHEMBL3539136 | 0.81 | DPP4 (0.33) | DPP4DPP7NPC1RAB9AMAPT | |
| SCHEMBL2470438 | 0.71 | DPP4 (0.51) | DPP4DPP7 | |
| SCHEMBL15740022 | 0.71 | DPP4 (0.42) | DPP4DPP7 | |
| SCHEMBL15739881 | 0.69 | DPP4 (0.46) | DPP4DPP7 | |
| Hydrochloric Acid SCHEMBL12476875 | 0.69 | DPP4 (0.46) | DPP4DPP7 | |
| SCHEMBL12476863 | 0.69 | DPP4 (0.33) | DPP4DPP7 | |
| SCHEMBL3532203 | 0.67 | DPP4 (0.35) | DPP4DPP7 | |
| SCHEMBL2469615 | 0.67 | DPP4 (0.38) | DPP4DPP7 | |
| SCHEMBL17137872 | 0.67 | DPP4 (0.33) | DPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819674-B1 | FUSED AMINOPIPERIDINES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK SHARP & DOHME (US) | 2011-10-05 | — | — | EP | disclosed |