Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470441 | 0.86 | DPP4 (0.35) | DPP4DPP7 | |
| SCHEMBL2472453 | 0.86 | DPP4 (0.42) | DPP4DPP7DPP9KCNH2CYP2D6 | |
| SCHEMBL2469615 | 0.81 | DPP4 (0.38) | DPP4DPP7DPP9DPP8KCNH2 | |
| SCHEMBL3532203 | 0.80 | DPP4 (0.35) | DPP4DPP7DPP9DPP8KCNH2 | |
| SCHEMBL15740022 | 0.75 | DPP4 (0.42) | DPP4DPP7DPP9DPP8KCNH2 | |
| SCHEMBL15739881 | 0.73 | DPP4 (0.46) | DPP4DPP7DPP9DPP8KCNH2 | |
| SCHEMBL12477297 | 0.73 | DPP4 (0.46) | DPP4DPP7DPP9DPP8KCNH2 | |
| Hydrochloric Acid SCHEMBL12476875 | 0.72 | DPP4 (0.46) | DPP4DPP7DPP9DPP8KCNH2 | |
| SCHEMBL15739900 | 0.69 | PADI4 (0.36) | DPP4DPP7DPP9 | |
| SCHEMBL2471776 | 0.69 | DPP4 (0.55) | DPP4DPP7DPP9DPP8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819674-B1 | FUSED AMINOPIPERIDINES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK SHARP & DOHME (US) | 2011-10-05 | — | — | EP | disclosed |