⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927490 | 0.86 | — | — | |
| SCHEMBL6844020 | 0.83 | — | — | |
| SCHEMBL18205537 | 0.81 | OPRM1 (0.57) | — | |
| SCHEMBL2388357 | 0.75 | — | — | |
| SCHEMBL26985884 | 0.74 | — | — | |
| SCHEMBL1469931 | 0.74 | — | — | |
| SCHEMBL27674365 | 0.74 | — | — | |
| SCHEMBL6545812 | 0.74 | METAP1 (0.36) | — | |
| SCHEMBL24017050 | 0.72 | OPRM1 (0.40) | — | |
| SCHEMBL580950 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107624113-B | Tetrahydropyridopyrimidines and tetrahydropyridopyridines as inhibitors of HBsAg (HBV surface antigen) and HBV DNA production for the treatment of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2020-10-23 | — | — | CN | claimed |
| US-11926779-B2 | Liquid crystal polyester and film comprising the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-03-12 | — | — | US | disclosed |
| US-20230295414-A1 | A SLOW REACTING RECYCLABLE EPOXY RESIN SYSTEM FOR STRUCTURAL COMPOSITES | ADITYA BIRLA CHEMICALS (THAILAND) LTD. (ADVANCED MATERIALS) (TH) | 2023-09-21 | — | — | US | disclosed |
| US-20230295512-A1 | LIQUID CRYSTAL POLYESTER AND FILM COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-09-21 | — | — | US | disclosed |
| US-20230295513-A1 | LIQUID CRYSTAL POLYESTER AND FILM COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-09-21 | — | — | US | disclosed |
| WO-2023145476-A1 | MICROPROCESSING TREATMENT AGENT AND MICROPROCESSING TREATMENT METHOD | ステラケミファ株式会社 | 2023-08-03 | — | — | WO | disclosed |
| US-20230201144-A1 | BIARYLSULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE FOR TREATING FIBROTIC LUNG DISEASE | NOVOMEDIX, LLC (US) | 2023-06-29 | — | — | US | disclosed |
| EP-4157249-A1 | BIARYLSULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE FOR TREATING FIBROTIC LUNG DISEASE | Novomedix, LLC (US) | 2023-04-05 | — | — | EP | disclosed |
| CN-114286833-A | Liquid crystal polyester, molded article, and method for producing liquid crystal polyester | 住友化学株式会社 | 2022-04-05 | — | — | CN | disclosed |
| WO-2021243319-A1 | BIARYLSULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE FOR TREATING FIBROTIC LUNG DISEASE | NOVOMEDIX, LLC (US) | 2021-12-02 | — | — | WO | disclosed |
| EP-0409414-A1 | Diaryl ether cycloalkanes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-23 | — | — | EP | disclosed |
| CN-1046529-A | Carbostyril derivative | OTSUKA PHARMA CO LTD (JP) | 1990-10-31 | — | — | CN | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |
| US-4767847-A | Nobamycin its analogs and process therefore | THE UPJOHN COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| US-4716242-A | ANTITUMOR AGENTS | ASTA-WERKE AKTIENGESELLSCHAFT CHEMISCHE FABRIK (DE) | 1987-12-29 | — | — | US | disclosed |
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| US-4439602-A | Nogalamycin derivatives | THE UPJOHN COMPANY (US) | 1984-03-27 | — | — | US | disclosed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |
| US-4318790-A | Photochemical process for preparing N-demethyl-derivatives of nogalamycin | THE UPJOHN COMPANY (US) | 1982-03-09 | — | — | US | disclosed |