SCHEMBL24705245

SCHEMBL24705245

O=C(NCC1CO1)C(Cc1cccc2c1oc1ccccc12)N1C(=O)c2cc(Oc3ccc(-c4ccccc4)cc3)c3c4c(Oc5ccc(-c6ccccc6)cc5)cc5c6c(cc(Oc7ccc(-c8ccccc8)cc7)c(c7c(Oc8ccc(-c9ccccc9)cc8)cc(c2c37)C1=O)c64)C(=O)N(C(Cc1cccc2c1oc1ccccc12)C(=O)NCC1CO1)C5=O

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 12/20 0.33
HDAC8 Q9BY41 1/20 0.32
KMT2A Q03164 3/20 0.32
DNMT1 P26358 2/20 0.32
CYP2C19 P33261 1/20 0.32
DNMT3B Q9UBC3 1/20 0.32
PKM P14618 1/20 0.32
KDM4E B2RXH2 2/20 0.31
MEN1 O00255 2/20 0.31
ALDH1A1 P00352 1/20 0.31
PRMT5 O14744 1/20 0.30
WDR77 Q9BQA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24705437 0.90 HDAC8 (0.34) HDAC8KMT2ADNMT1CYP2C19DNMT3B
SCHEMBL24705423 0.89 EDNRB (0.33) EDNRBHDAC8KMT2ADNMT1CYP2C19
SCHEMBL24704967 0.88 EDNRB (0.33) EDNRBHDAC8KMT2ADNMT1CYP2C19
SCHEMBL24705661 0.84 SMN1; SMN2 (0.34) HDAC8CYP2C19KDM4EALDH1A1
SCHEMBL24705144 0.80 SMN1; SMN2 (0.39) KMT2AALDH1A1
SCHEMBL24704880 0.80 HDAC8 (0.31) HDAC8KDM4EALDH1A1
SCHEMBL24704920 0.79 KMT2A (0.44) KMT2APKMMEN1ALDH1A1
SCHEMBL24704947 0.79 HDAC8 (0.34) EDNRBHDAC8KMT2ADNMT1CYP2C19
SCHEMBL24705491 0.78 DNMT1 (0.33) HDAC8KMT2ADNMT1KDM4E
SCHEMBL24705673 0.76 KMT2A (0.41) KMT2APKMKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220389014-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM MANUFACTURED THEREFROM, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD. (KR) 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220389014-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM MANUFACTURED THEREFROM, BACKLIGHT UNIT, AND DISPLAY DEVICE NOTUM, THEM6, FAR1 EDNRB 4822/4885HDAC8 4721/4885KMT2A 2312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.