Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 18/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 15/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25059967 | 0.81 | CARM1 (0.55) | CARM1PRMT5WDR77 | |
| SCHEMBL5862011 | 0.79 | KMT2A (0.61) | PRMT5WDR77 | |
| SCHEMBL22255845 | 0.79 | CARM1 (0.46) | CARM1PRMT5WDR77 | |
| SCHEMBL29436807 | 0.79 | CARM1 (0.46) | CARM1PRMT5WDR77 | |
| SCHEMBL5546764 | 0.77 | HDAC3 (0.68) | PRMT5WDR77 | |
| SCHEMBL24066060 | 0.77 | CARM1 (0.70) | CARM1PRMT5WDR77 | |
| SCHEMBL31688915 | 0.75 | PRMT5 (0.57) | CARM1PRMT5WDR77 | |
| SCHEMBL31369623 | 0.75 | PRMT5 (0.57) | CARM1PRMT5WDR77 | |
| SCHEMBL18212446 | 0.74 | CARM1 (0.57) | CARM1PRMT5WDR77 | |
| SCHEMBL28655189 | 0.74 | CARM1 (0.57) | CARM1PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911645-B1 | 5-MEMBERED HETEROARYL COMPOUNDS CONTAINING A HYDROXAMATE MOIETY AND THEIR USE | UNIV LILLE (FR) | 2022-12-07 | — | — | EP | disclosed |