⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761699 | 1.00 | — | — | |
| SCHEMBL28138878 | 0.87 | — | — | |
| SCHEMBL16638023 | 0.86 | — | — | |
| SCHEMBL761898 | 0.85 | — | — | |
| SCHEMBL6743851 | 0.83 | — | — | |
| SCHEMBL12988554 | 0.81 | — | — | |
| SCHEMBL21779915 | 0.81 | — | — | |
| SCHEMBL28194588 | 0.81 | — | — | |
| SCHEMBL1515122 | 0.81 | — | — | |
| SCHEMBL2420834 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192145-A1 | MAP4K1 INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2022-09-15 | — | — | WO | disclosed |