⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761699 | 0.85 | — | — | |
| SCHEMBL24707652 | 0.85 | — | — | |
| SCHEMBL25202184 | 0.79 | — | — | |
| SCHEMBL28138878 | 0.78 | — | — | |
| SCHEMBL1515150 | 0.77 | — | — | |
| SCHEMBL1168562 | 0.77 | — | — | |
| SCHEMBL17630555 | 0.77 | — | — | |
| SCHEMBL17645041 | 0.77 | — | — | |
| SCHEMBL16638023 | 0.77 | — | — | |
| SCHEMBL3182655 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018120-A1 | MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2024-01-18 | — | — | US | disclosed |
| WO-2023114823-A1 | BENZOTHIOPHENE DERIVATIVES AS RXFP1 AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2017147526-A1 | PI-KINASE INHIBITORS WITH ANTI-INFECTIVE ACTIVITY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-08-31 | — | — | WO | disclosed |
| EP-2114951-B9 | NOVEL PHOSPHODIESTERASE INHIBITORS | LEO PHARMA AS (DK) | 2015-09-02 | — | — | EP | disclosed |
| EP-2881394-A1 | CONDENSED RING HETEROCYCLIC COMPOUND | Kyowa Hakko Kirin Co., Ltd. (JP) | 2015-06-10 | — | — | EP | disclosed |
| CN-101631792-B | Novel phosphodiesterase inhibitors | LEO PHARMA AS DK | 2013-05-01 | — | — | CN | disclosed |
| US-8338431-B2 | Phosphodiesterase inhibitors | LEO PHARMA A/S (DK) | 2012-12-25 | — | — | US | disclosed |
| EP-1567678-B1 | PROCESS FOR TANNING AND TANNING AGENT | TFL LEDERTECHNIK GMBH (DE) | 2012-03-21 | — | — | EP | disclosed |
| US-20100099688-A1 | NOVEL PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2010-04-22 | — | — | US | disclosed |
| CN-101631792-A | Novel phosphodiesterase inhibitors | LEO PHARMA AS | 2010-01-20 | — | — | CN | disclosed |
| EP-2114951-A2 | NOVEL PHOSPHODIESTERASE INHIBITORS | Leo Pharma A/S (DK) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008104175-A2 | NOVEL PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2008-09-04 | — | — | WO | disclosed |
| EP-1567678-A1 | PROCESS FOR TANNING AND TANNING AGENT | TFL Ledertechnik GmbH (DE) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004053170-A1 | PROCESS FOR TANNING AND TANNING AGENT | TFL LEDERTECHNIK GMBH (DE) | 2004-06-24 | — | — | WO | disclosed |