SCHEMBL2470816

COC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](O)[C@]1(O)OP(O)(=S)OC(O)[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H]1O

nearest known ligand 0.44

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY2	P41231	12/20	0.44

▸	P2RY4	P51582	6/20	0.44

▸	P2RY14	Q15391	5/20	0.44

▸	P2RY6	Q15077	8/20	0.44

▸	ENPP1	P22413	2/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2470818	0.86	SLC28A1 (0.43)	P2RY2P2RY4P2RY14P2RY6ENPP1
SCHEMBL16495246	0.86	SLC28A1 (0.43)	P2RY2P2RY4P2RY14P2RY6ENPP1
SCHEMBL16495245	0.86	SLC28A1 (0.43)	P2RY2P2RY4P2RY14P2RY6ENPP1
SCHEMBL2474494	0.85	SLC28A1 (0.45)	P2RY2P2RY4P2RY14P2RY6ENPP1
SCHEMBL2474507	0.85	SLC28A1 (0.45)	P2RY2P2RY4P2RY14P2RY6ENPP1
SCHEMBL16495068	0.85	SLC28A1 (0.45)	P2RY2P2RY4P2RY14P2RY6ENPP1
SCHEMBL2471085	0.81	SLC28A1 (0.41)	P2RY2P2RY4P2RY14P2RY6ENPP1
SCHEMBL2470251	0.79	RNASEL (0.51)	P2RY2ENPP1
SCHEMBL2470248	0.79	RNASEL (0.51)	P2RY2ENPP1
SCHEMBL2470239	0.79	RNASEL (0.51)	P2RY2ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2370451-A2	METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS	Chiralgen, Ltd. (JP)	2011-10-05	—	—	EP	disclosed
WO-2010064146-A2	METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS	CHIRALGEN, LTD. (JP)	2010-06-10	—	—	WO	disclosed