Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 7/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | MDM4 | O15151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26195497 | 1.00 | MDM2 (0.53) | MDM2TLR2MDM4TP53SLC17A5 | |
| SCHEMBL26195496 | 0.91 | MDM2 (0.50) | MDM2TLR2MDM4TP53SLC17A5 | |
| SCHEMBL10417439 | 0.85 | TLR2 (0.55) | MDM2TLR2MDM4TP53SLC17A5 | |
| SCHEMBL30863678 | 0.85 | TLR2 (0.55) | MDM2TLR2MDM4TP53SLC17A5 | |
| SCHEMBL31619571 | 0.80 | MDM2 (0.49) | MDM2TLR2MDM4TP53SLC17A5 | |
| SCHEMBL30863677 | 0.80 | MDM2 (0.49) | MDM2TLR2MDM4TP53TNF | |
| SCHEMBL10418082 | 0.80 | MDM2 (0.49) | MDM2TLR2MDM4TP53TNF | |
| SCHEMBL13227673 | 0.78 | TLR2 (0.57) | MDM2TLR2MDM4TP53SLC17A5 | |
| SCHEMBL29401420 | 0.78 | TLR2 (0.57) | MDM2TLR2MDM4TP53SLC17A5 | |
| SCHEMBL21597893 | 0.78 | TLR2 (0.57) | MDM2TLR2MDM4TP53SLC17A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261257-A1 | STAPLED PEPTIDES AND METHODS THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |