Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 3/20 | 0.49 |
| ▸ | MDM4 | O15151 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30863677 | 1.00 | MDM2 (0.49) | MDM2MDM4TP53CASP3PTPN1 | |
| SCHEMBL10417439 | 0.91 | TLR2 (0.55) | MDM2MDM4TP53CASP3PTPN1 | |
| SCHEMBL30863678 | 0.91 | TLR2 (0.55) | MDM2MDM4TP53CASP3PTPN1 | |
| SCHEMBL26195496 | 0.85 | MDM2 (0.50) | MDM2MDM4TP53CASP3TLR2 | |
| SCHEMBL31111403 | 0.83 | TAS1R3 (0.48) | MDM2TP53 | |
| SCHEMBL10417444 | 0.83 | PTPN1 (0.56) | PTPN1 | |
| SCHEMBL29561499 | 0.80 | MDM2 (0.56) | MDM2MDM4TP53CASP3TLR2 | |
| SCHEMBL119621 | 0.80 | MDM2 (0.56) | MDM2MDM4TP53CASP3TLR2 | |
| SCHEMBL24709082 | 0.80 | MDM2 (0.53) | MDM2MDM4TP53CASP3TLR2 | |
| SCHEMBL26195497 | 0.80 | MDM2 (0.53) | MDM2MDM4TP53CASP3TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935536-A | TRIALKOXYBENZYL PROTECTED AMINO ACID | MILLIPORE CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| EP-0292228-A2 | Protecting groups for asparagine and glutamine in peptide synthesis | MILLIPORE CORPORATION (US) | 1988-11-23 | — | — | EP | disclosed |