Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 4/20 | 0.82 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.82 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24708728 | 1.00 | CACNA1G (0.82) | CACNA1GCACNA1HCYP2D6CYP3A4DRD2 | |
| SCHEMBL31000419 | 1.00 | CACNA1G (0.82) | CACNA1GCACNA1HCYP2D6CYP3A4DRD2 | |
| SCHEMBL24709560 | 0.98 | CACNA1G (0.78) | CACNA1GCACNA1HCYP2D6CYP3A4DRD2 | |
| SCHEMBL24708732 | 0.91 | CACNA1G (0.87) | CACNA1GCACNA1HCYP2D6CYP3A4DRD2 | |
| SCHEMBL24709338 | 0.91 | CACNA1G (0.87) | CACNA1GCACNA1HCYP2D6CYP3A4DRD2 | |
| SCHEMBL30079694 | 0.91 | CACNA1G (1.00) | CACNA1GCACNA1HCYP2D6CYP3A4DRD2 | |
| SCHEMBL24708724 | 0.91 | CACNA1G (1.00) | CACNA1GCACNA1HCYP2D6CYP3A4DRD2 | |
| SCHEMBL24709353 | 0.90 | CACNA1G (0.78) | CACNA1GCACNA1HCYP2D6CYP3A4DRD2 | |
| SCHEMBL24708751 | 0.90 | CACNA1G (0.78) | CACNA1GCACNA1HCYP2D6CYP3A4DRD2 | |
| SCHEMBL24709104 | 0.90 | CACNA1G (0.98) | CACNA1GCACNA1HCYP2D6CYP3A4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4353713-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | Kinki University (JP) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022260016-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | 学校法人近畿大学 | 2022-12-15 | — | — | WO | disclosed |