Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 5/20 | 0.38 |
| ▸ | CHRM3 known ✓ | P20309 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10881754 | 0.90 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11024591 | 0.90 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28045898 | 0.88 | TSHR (0.44) | TSHRHPGDALDH1A1TP53HIF1A | |
| Methylsulfanylmethane SCHEMBL10483613 | 0.88 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL1598545 | 0.87 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL5154567 | 0.87 | TSHR (0.46) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL6401478 | 0.87 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL304033 | 0.86 | TSHR (0.43) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL2733907 | 0.86 | TSHR (0.53) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL27659543 | 0.85 | CHRM5 (0.44) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054923-B1 | RAPID SET LATEXES AND FOAMED ARTICLES PREPARED THEREFROM | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-03-12 | — | — | EP | claimed |
| US-6025404-A | FROTHING A LATEX THAT CONTAINS A DISPERSED POLYMER HAVING PENDANT CATIONIC GROUPS OR ADSORBING CATIONIC MOLECULES OR BOTH, AND PENDANT ACID GROUPS; AND B) RENDERING THE FROTHED LATEX SUFFICIENTLY BASIC TO MAKE THE CELLULAR ARTICLE. | THE DOW CHEMICAL COMPANY (US) | 2000-02-15 | — | — | US | claimed |
| CN-1043372-C | Gelation of water soluble polymers | PHILLIPS PETROLEUM CO (US) | 1999-05-12 | — | — | CN | claimed |
| EP-0566028-B1 | Gelable compositions of water soluble polymers | PHILLIPS PETROLEUM CO (US) | 1996-05-22 | — | — | EP | claimed |
| EP-0475325-B1 | Gelatin of acrylamide-containing polymers with aminobenzoic acid compounds and water dispersible aldehydes | PHILLIPS PETROLEUM CO (US) | 1995-04-19 | — | — | EP | claimed |
| EP-0446865-B1 | Gelation of acrylamide-containing polymers with hydroxyphenyl alkanols | PHILLIPS PETROLEUM CO (US) | 1994-09-21 | — | — | EP | claimed |
| EP-0447967-B1 | Gelation of acrylamide-containing polymers with furfuryl alcohol and water dispersible aldehydes | PHILLIPS PETROLEUM CO (US) | 1994-05-18 | — | — | EP | claimed |
| EP-0566028-A1 | Gelable compositions of water soluble polymers | PHILLIPS PETROLEUM COMPANY (US) | 1993-10-20 | — | — | EP | claimed |
| CN-1077467-A | The gelation of water-soluble polymers | PHILLIPS PETROLEUM CO (US) | 1993-10-20 | — | — | CN | claimed |
| US-5179136-A | Enhanced or recovery operations | PHILLIPS PETROLEUM COMPANY (US) | 1993-01-12 | — | — | US | claimed |
| US-5100931-A | Crosslinking; enhanced oil recovery | PHILLIPS PETROLEUM COMPANY (US) | 1992-03-31 | — | — | US | claimed |
| EP-0475325-A1 | Gelatin of acrylamide-containing polymers with aminobenzoic acid compounds and water dispersible aldehydes | PHILLIPS PETROLEUM COMPANY (US) | 1992-03-18 | — | — | EP | claimed |
| EP-0447967-A2 | Gelation of acrylamide-containing polymers with furfuryl alcohol and water dispersible aldehydes | PHILLIPS PETROLEUM COMPANY (US) | 1991-09-25 | — | — | EP | claimed |
| EP-0446865-A2 | Gelation of acrylamide-containing polymers with hydroxyphenyl alkanols | PHILLIPS PETROLEUM COMPANY (US) | 1991-09-18 | — | — | EP | claimed |
| US-5043364-A | Adjusting permeability of well bores | PHILLIPS PETROLEUM COMPANY (US) | 1991-08-27 | — | — | US | claimed |
| US-5006596-A | Flocculation | BETZ LABORATORIES, INC. (US) | 1991-04-09 | — | — | US | claimed |
| EP-0280083-B1 | DELAYING THE GELATION OF WATER SOLUBLE POLYMERS | PHILLIPS PETROLEUM COMPANY (US) | 1990-10-31 | — | — | EP | claimed |
| US-4822842-A | WITH TRANSITION METAL IONS; ENHANCED OIL RECOVERY | PHILLIPS PETROLEUM COMPANY (US) | 1989-04-18 | — | — | US | claimed |
| EP-0280083-A1 | Delaying the gelation of water soluble polymers | PHILLIPS PETROLEUM COMPANY (US) | 1988-08-31 | — | — | EP | claimed |
| US-4055502-A | Method and composition for acidizing subterranean formations | PHILLIPS PETROLEUM COMPANY (US) | 1977-10-25 | — | — | US | claimed |