Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 6/20 | 0.44 |
| ▸ | CHRM3 known ✓ | P20309 | 5/20 | 0.44 |
| ▸ | CHRM2 known ✓ | P08172 | 4/20 | 0.41 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.44 |
| ▸ | SCN1A | P35498 | 2/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1598545 | 0.98 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A | |
| Chloromethane SCHEMBL632241 | 0.95 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| Methylsulfanylmethane SCHEMBL10483613 | 0.95 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL10483610 | 0.95 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL14335996 | 0.91 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL5451161 | 0.89 | TSHR (0.59) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL31509595 | 0.88 | TSHR (0.56) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27553632 | 0.87 | TSHR (0.61) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL5456445 | 0.87 | TSHR (0.56) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11024591 | 0.87 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798541-A | Modified reinforcing agent and preparation method and application thereof | 九洲生物技术（苏州）有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-119798542-A | Guar gum modified reinforcing agent and preparation method and application thereof | 九洲生物技术（苏州）有限公司 | 2025-04-11 | — | — | CN | claimed |
| EP-2720668-B1 | COSMETIC USE OF A FLOCCULANT POLYMER AS ANTIPERSPIRANT | OREAL (FR) | 2020-05-06 | — | — | EP | claimed |
| US-20070248551-A1 | Use as an Antiperspirant Agent of a Flocculating Water-Soluble Polymer; Cosmetic Process for Treating Perspiration | L'OREAL S.A. (FR) | 2007-10-25 | — | — | US | claimed |
| EP-1761241-A1 | USE AS AN ANTIPERSPIRANT AGENT OF A FLOCCULATING WATER-SOLUBLE POLYMER; COSMETIC PROCESS FOR TREATING PERSPIRATION | l'Oreal SA (FR) | 2007-03-14 | — | — | EP | claimed |
| WO-2005120448-A1 | USE AS AN ANTIPERSPIRANT AGENT OF A FLOCCULATING WATER-SOLUBLE POLYMER; COSMETIC PROCESS FOR TREATING PERSPIRATION | L'OREAL (FR) | 2005-12-22 | — | — | WO | claimed |
| US-5952394-A | A SYNERGISTIC ANTIDEPOSIT AGENT MIXTURE COMPRISING A PARTIALLY HYDROLYZED POLYVINYL ALCOHOL, A HIGH MOLECULAR WEIGHT GELATIN AND A CATIONIC POLYMER | BETZDEARBORN INC. (US) | 1999-09-14 | — | — | US | claimed |
| EP-0900299-A1 | COMPOSITIONS AND METHODS FOR INHIBITING DEPOSITS IN PULP AND PAPERMAKING SYSTEMS | BetzDearborn Inc (US) | 1999-03-10 | — | — | EP | claimed |
| EP-0900299-A4 | — | — | 1999-03-10 | — | — | EP | claimed |
| US-5723021-A | POLYVINYL ALCOHOL, GELATIN AND CATIONIC POLYMER | BETZDEARBORN INC. (US) | 1998-03-03 | — | — | US | claimed |
| WO-1997044519-A1 | COMPOSITIONS AND METHODS FOR INHIBITING DEPOSITS IN PULP AND PAPERMAKING SYSTEMS | BETZDEARBORN INC. (US) | 1997-11-27 | — | — | WO | claimed |
| CN-115850602-B | Lithium ion battery anode slurry dispersing agent and preparation method thereof | 深圳好电科技有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-119798541-A | Modified reinforcing agent and preparation method and application thereof | 九洲生物技术（苏州）有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-119798542-A | Guar gum modified reinforcing agent and preparation method and application thereof | 九洲生物技术（苏州）有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-115298110-B | Cover tape for packaging electronic component and package | 大日本印刷株式会社 | 2024-02-02 | — | — | CN | disclosed |
| US-5169540-A | Treating an aqueous system to separate suspended material | BETZ LABORATORIES, INC. (US) | 1992-12-08 | — | — | US | disclosed |
| US-5100951-A | Stable blends of cationic water-in-oil emulsion polymers and cationic aqueous solution polymers | BETZ LABORATORIES, INC. (US) | 1992-03-31 | — | — | US | disclosed |
| EP-0083984-B1 | PREPARATION OF STABLE AQUEOUS DISPERSIONS OF POLYOLEFIN FIBRES | HERCULES INCORPORATED (US) | 1986-04-30 | — | — | EP | disclosed |
| US-4404314-A | CATIONIC COPOLYMER OF ACRYLAMIDE AND ACRYLATE | HERCULES INCORPORATED (US) | 1983-09-13 | — | — | US | disclosed |
| EP-0083984-A1 | Preparation of stable aqueous dispersions of polyolefin fibres | HERCULES INCORPORATED (US) | 1983-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070248551-A1 | Use as an Antiperspirant Agent of a Flocculating Water-Soluble Polymer; Cosmetic Process for Treating Perspiration | CUTA, TYR, PRKDC | CHRM1 755/4885CHRM3 1174/4885CHRM2 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.