Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.61 |
| ▸ | CA12 | O43570 | 9/20 | 0.61 |
| ▸ | CA1 | P00915 | 9/20 | 0.61 |
| ▸ | CA9 | Q16790 | 7/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16687927 | 1.00 | CA2 (0.61) | CA2CA12CA1CA9THRB | |
| SCHEMBL16441853 | 1.00 | CA2 (0.61) | CA2CA12CA1CA9THRB | |
| SCHEMBL18857678 | 1.00 | CA2 (0.61) | CA2CA12CA1CA9THRB | |
| SCHEMBL14160416 | 1.00 | CA2 (0.61) | CA2CA12CA1CA9THRB | |
| SCHEMBL24149171 | 1.00 | CA2 (0.61) | CA2CA12CA1CA9THRB | |
| SCHEMBL1755348 | 1.00 | CA2 (0.61) | CA2CA12CA1CA9THRB | |
| SCHEMBL9539592 | 1.00 | CA2 (0.61) | CA2CA12CA1CA9THRB | |
| SCHEMBL5792080 | 1.00 | CA2 (0.61) | CA2CA12CA1CA9THRB | |
| SCHEMBL13163856 | 1.00 | CA2 (0.61) | CA2CA12CA1CA9THRB | |
| SCHEMBL8429613 | 1.00 | CA2 (0.61) | CA2CA12CA1CA9THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250327-A1 | TREATMENT OF GPAM RELATED DISEASES AND DISORDERS | EMPIRICO INC. (US) | 2023-12-28 | — | — | WO | disclosed |
| WO-2022266037-A1 | TREATMENT OF MST1 RELATED DISEASES AND DISORDERS | EMPIRICO INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| WO-2022261005-A1 | TREATMENT OF ANGPTL4 RELATED DISEASES | EMPIRICO INC. (US) | 2022-12-15 | — | — | WO | disclosed |