Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND1 | P24385 | 10/20 | 0.53 |
| ▸ | CDK6 | Q00534 | 10/20 | 0.53 |
| ▸ | HTR6 | P50406 | 8/20 | 0.40 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24710411 | 0.80 | CCND1 (0.51) | CCND1CDK6CDK4 | |
| SCHEMBL22695244 | 0.79 | ELANE (0.43) | CCND1CDK6HTR6TYK2 | |
| SCHEMBL30748667 | 0.79 | ELANE (0.43) | CCND1CDK6HTR6TYK2 | |
| SCHEMBL24710122 | 0.77 | CCND1 (0.53) | CCND1CDK6TYK2CDK4 | |
| SCHEMBL24710243 | 0.76 | CCND1 (0.51) | CCND1CDK6CDK4 | |
| SCHEMBL24710134 | 0.73 | CCND1 (0.54) | CCND1CDK6CDK4 | |
| SCHEMBL28839294 | 0.73 | ASH1L (0.37) | HTR6 | |
| SCHEMBL24710386 | 0.70 | CCND1 (0.38) | CCND1CDK6 | |
| SCHEMBL518274 | 0.69 | CDK5 (0.51) | — | |
| SCHEMBL30337550 | 0.69 | CDK5 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257568-A1 | AZAINDOLE PYRIMIDINAMINE HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2022-12-15 | — | — | WO | disclosed |