Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND1 | P24385 | 15/20 | 0.51 |
| ▸ | CDK6 | Q00534 | 15/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24710411 | 0.85 | CCND1 (0.51) | CCND1CDK6DYRK1AGSK3BCDK4 | |
| SCHEMBL24710134 | 0.83 | CCND1 (0.54) | CCND1CDK6CDK4 | |
| SCHEMBL24710122 | 0.82 | CCND1 (0.53) | CCND1CDK6CDK4 | |
| SCHEMBL28679848 | 0.81 | RPS6KA5 (0.42) | CCND1CDK6DYRK1ARPS6KA5 | |
| SCHEMBL24710433 | 0.76 | CCND1 (0.53) | CCND1CDK6CDK4 | |
| SCHEMBL24710386 | 0.75 | CCND1 (0.38) | CCND1CDK6RPS6KA5 | |
| SCHEMBL30337550 | 0.74 | CDK5 (0.51) | — | |
| SCHEMBL518274 | 0.74 | CDK5 (0.51) | — | |
| SCHEMBL17490424 | 0.72 | RPS6KA5 (0.54) | CCND1CDK6DYRK1AGSK3BRPS6KA5 | |
| SCHEMBL26076475 | 0.71 | DYRK1A (0.58) | DYRK1APRKCBGSK3BCES2TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257568-A1 | AZAINDOLE PYRIMIDINAMINE HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2022-12-15 | — | — | WO | disclosed |