Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.74 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.74 |
| ▸ | POLB | P06746 | 3/20 | 0.74 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 8/20 | 0.71 |
| ▸ | TP53 | P04637 | 3/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16602324 | 0.84 | TP53 (0.75) | MEN1KMT2AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL12963193 | 0.84 | MEN1 (0.72) | MEN1KMT2AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL12963427 | 0.84 | MAPT (0.70) | MEN1KMT2AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL12963192 | 0.83 | TP53 (0.69) | MEN1KMT2AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL12963202 | 0.82 | TP53 (0.71) | MEN1KMT2AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL12963458 | 0.80 | SMN1; SMN2 (0.85) | MEN1KMT2AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL24711450 | 0.80 | MAPT (0.69) | MEN1KMT2AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL12981158 | 0.78 | MAPT (0.71) | MEN1KMT2AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL12963468 | 0.78 | MAPT (0.76) | MEN1KMT2AALDH1A1KDM4ECYP3A4 | |
| SCHEMBL13173972 | 0.78 | MAPT (0.78) | MEN1KMT2AALDH1A1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220395500-A1 | SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF | NEURALEXO, INC. | 2022-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220395500-A1 | SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF | IRF3, IRF2BP2, STAT1 | MEN1 4664/4885KMT2A 3862/4885ALDH1A1 4853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.