Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.70 |
| ▸ | MAPT | P10636 | 11/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | TNF | P01375 | 1/20 | 0.68 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.68 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | HTR1E | P28566 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24710972 | 0.94 | MAPT (0.74) | KMT2AKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24710952 | 0.87 | MAPT (0.70) | KMT2AKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24711208 | 0.83 | RAB9A (0.69) | KMT2AKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24711233 | 0.82 | MAPT (0.70) | KMT2AKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24710800 | 0.81 | MAPT (0.68) | KMT2AKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24711140 | 0.81 | MAPT (0.63) | KMT2AKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24710796 | 0.79 | MAPT (0.75) | KMT2AKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24711237 | 0.78 | MAPT (0.68) | KMT2AKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24710978 | 0.78 | MAPT (0.65) | KMT2AKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27868424 | 0.76 | RAB9A (0.71) | KMT2AKDM4EMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220395500-A1 | SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF | NEURALEXO, INC. | 2022-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220395500-A1 | SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF | IRF3, IRF2BP2, STAT1 | KMT2A 3862/4885KDM4E 2942/4885MAPT 4038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.