Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 20/20 | 0.43 |
| ▸ | CDK2 | P24941 | 20/20 | 0.43 |
| ▸ | CCND1 | P24385 | 19/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 19/20 | 0.43 |
| ▸ | CDK4 | P11802 | 3/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.42 |
| ▸ | CDK9 | P50750 | 2/20 | 0.42 |
| ▸ | CCND3 | P30281 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4826111 | 0.86 | OPRM1 (0.42) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL29594767 | 0.86 | OPRM1 (0.42) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL25907793 | 0.79 | CCNE1 (0.58) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL25907827 | 0.79 | CCNE1 (0.58) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL19857394 | 0.79 | CCND1 (0.59) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL30550184 | 0.77 | CCNE1 (0.51) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL29990631 | 0.77 | CCND1 (0.51) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL22860690 | 0.76 | CCNE1 (0.46) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL29507797 | 0.76 | CCNE1 (0.46) | CCNE1CDK2CCND1CDK6CDK4 | |
| SCHEMBL29991117 | 0.76 | CCND1 (0.61) | CCNE1CDK2CCND1CDK6CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022258023-A1 | COMPOUND AS CDK KINASE INHIBITOR AND USE THEREOF | 郑州同源康医药有限公司 | 2022-12-15 | — | — | WO | disclosed |