Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.72 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24710948 | 0.88 | MAPT (0.61) | MAPTSMN1; SMN2ALOX15ALOX12NR4A1 | |
| SCHEMBL24710828 | 0.87 | MAPT (0.74) | MAPTSMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL13856442 | 0.84 | MAPT (1.00) | MAPTSMN1; SMN2ALOX15ALOX12NR4A1 | |
| SCHEMBL24711233 | 0.81 | MAPT (0.70) | MAPTSMN1; SMN2ALOX12ALDH1A1KDM4E | |
| SCHEMBL24711140 | 0.80 | MAPT (0.63) | MAPTSMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL24710756 | 0.79 | MAPT (0.59) | MAPTALOX15HSD17B10ALDH1A1KDM4E | |
| SCHEMBL24711208 | 0.79 | RAB9A (0.69) | MAPTSMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL24711152 | 0.79 | MAPT (0.77) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL24710977 | 0.77 | KMT2A (0.67) | MAPTSMN1; SMN2ALOX12ALDH1A1KDM4E | |
| SCHEMBL24710800 | 0.77 | MAPT (0.68) | MAPTSMN1; SMN2ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220395500-A1 | SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF | NEURALEXO, INC. | 2022-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220395500-A1 | SMALL MOLECULE ACTIVATORS OF INTERFERON REGULATORY FACTOR 3 AND METHODS OF USE THEREOF | IRF3, IRF2BP2, STAT1 | MAPT 4038/4885SMN1; SMN2 1343/4885ALOX15 3780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.