SCHEMBL24711490

SCHEMBL24711490

Cc1ccccc1C(c1ccccc1)c1ccc(O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
GAA P10253 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
KMT2A Q03164 1/20 0.56
ACP3 P15309 1/20 0.47
IDO1 P14902 1/20 0.43
TDO2 P48775 1/20 0.43
ESR1 P03372 2/20 0.41
TYR P14679 1/20 0.41
PDCD1 Q15116 1/20 0.40
ESR2 Q92731 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
OPRM1 P35372 4/20 0.38
CYP2D6 P10635 2/20 0.38
SLC22A2 O15244 1/20 0.38
SLC22A1 O15245 1/20 0.38
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465062 0.96 ALDH1A1 (0.55) ALDH1A1GAATDP1KMT2AACP3
SCHEMBL2422170 0.88 ACP3 (0.52) GAAKMT2AACP3ESR1OPRM1
Dimethylamine SCHEMBL11331424 0.87 ALDH1A1 (0.46) ALDH1A1GAATDP1KMT2AACP3
SCHEMBL5270216 0.83 ACP3 (0.52) GAAACP3ESR1OPRM1CYP2D6
SCHEMBL1758062 0.81 TDP1 (0.64) ALDH1A1GAATDP1KMT2AIDO1
SCHEMBL11758370 0.81 TYR (0.49) ALDH1A1GAATDP1KMT2AACP3
SCHEMBL982047 0.79 IDO1 (0.56) ALDH1A1GAATDP1KMT2AIDO1
SCHEMBL22694327 0.79 IDO1 (0.56) ALDH1A1GAATDP1KMT2AIDO1
SCHEMBL36791 0.79 IDO1 (0.56) ALDH1A1GAATDP1KMT2AIDO1
SCHEMBL19314626 0.79 IDO1 (0.56) ALDH1A1GAATDP1KMT2AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022257962-A1 FRICTION-RESISTANT HIGH SHEAR RESISTANT COMPOSITE RUBBER SEALING MATERIAL 四川大学 2022-12-15 WO disclosed