Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24095376 | 1.00 | HPGD (0.45) | HPGDUSP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3940936 | 1.00 | HPGD (0.45) | HPGDUSP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31460589 | 0.95 | HPGD (0.48) | HPGDUSP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31603608 | 0.95 | HPGD (0.48) | HPGDUSP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31460689 | 0.95 | HPGD (0.48) | HPGDUSP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25286793 | 0.90 | USP2 (0.47) | HPGDUSP2SMN1; SMN2EPHX1MAPT | |
| SCHEMBL2218646 | 0.90 | USP2 (0.47) | HPGDUSP2SMN1; SMN2EPHX1MAPT | |
| SCHEMBL5524618 | 0.87 | HPGD (0.49) | HPGDUSP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12683369 | 0.86 | HPGD (0.47) | HPGDUSP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14801055 | 0.86 | USP2 (0.50) | HPGDUSP2SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026047575-A1 | HYDROQUINAZOLINE DERIVATIVES FOR THE TREATMENT OF A DISEASE OR DISORDER | NOVARTIS AG (CH) | 2026-03-05 | — | — | WO | disclosed |
| WO-2025087282-A1 | METHOD FOR PREPARING CHIRAL ALCOHOL COMPOUND | 中国科学院上海有机化学研究所 | 2025-05-01 | — | — | WO | disclosed |
| CN-119899090-A | Preparation method of chiral alcohol compound | 中国科学院上海有机化学研究所 | 2025-04-29 | — | — | CN | disclosed |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics | 2023-10-26 | — | — | US | disclosed |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics | 2023-10-26 | — | — | US | disclosed |
| WO-2022258986-A1 | COMPOUNDS USEFUL IN THE TREATMENT OR PREVENTION OF A PRMT5-MEDIATED DISORDER | Argonaut Therapeutics Limited (GB) | 2022-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | SREBF1, SREBF2, NR1H3 | HPGD 987/4885USP2 2291/4885SMN1; SMN2 4785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.