Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31460589 | 1.00 | HPGD (0.48) | HPGDUSP2SMN1; SMN2PREPMEN1 | |
| SCHEMBL31460689 | 1.00 | HPGD (0.48) | HPGDUSP2SMN1; SMN2PREPMEN1 | |
| SCHEMBL24095376 | 0.95 | HPGD (0.45) | HPGDUSP2SMN1; SMN2PREPMEN1 | |
| SCHEMBL24711544 | 0.95 | HPGD (0.45) | HPGDUSP2SMN1; SMN2PREPMEN1 | |
| SCHEMBL3940936 | 0.95 | HPGD (0.45) | HPGDUSP2SMN1; SMN2PREPMEN1 | |
| SCHEMBL21145918 | 0.89 | HPGD (0.56) | HPGDUSP2SMN1; SMN2PREPMEN1 | |
| SCHEMBL21142647 | 0.89 | HPGD (0.56) | HPGDUSP2SMN1; SMN2PREPMEN1 | |
| SCHEMBL25286793 | 0.88 | USP2 (0.47) | HPGDUSP2SMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL2218646 | 0.88 | USP2 (0.47) | HPGDUSP2SMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL8265979 | 0.87 | HPGD (0.50) | HPGDUSP2SMN1; SMN2PREPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025107579-A1 | COMPOUND TARGETING UBIQUITIN KRAS PROTEIN DEGRADATION AGENT, AND USE THEREOF | 贝达药业股份有限公司 | 2025-05-30 | — | — | WO | disclosed |