SCHEMBL24711913

SCHEMBL24711913

O=C(O)CCCCCCCCCCCCCCC(=O)NC(CCCCNC(=O)CCOCCOCCNC(=O)CCOCCOCCNC(=O)[C@H](CCCNC(=O)CBr)NC(=O)CBr)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.65
▸ FOLH1 Q04609 7/20 0.47
▸ NOD1 Q9Y239 1/20 0.41
▸ GLO1 Q04760 1/20 0.40
▸ EPOR P19235 1/20 0.39
▸ FNTA P49354 1/20 0.39
▸ FNTB P49356 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24712871 1.00 GLP1R (0.65) GLP1RFOLH1NOD1GLO1EPOR
SCHEMBL23489667 1.00 GLP1R (0.65) GLP1RFOLH1NOD1GLO1EPOR
SCHEMBL18202847 1.00 GLP1R (0.65) GLP1RFOLH1NOD1GLO1EPOR
SCHEMBL27435532 1.00 GLP1R (0.65) GLP1RFOLH1NOD1GLO1EPOR
SCHEMBL23475917 1.00 GLP1R (0.65) GLP1RFOLH1NOD1GLO1EPOR
SCHEMBL23475915 1.00 GLP1R (0.65) GLP1RFOLH1NOD1GLO1EPOR
SCHEMBL23475960 1.00 GLP1R (0.65) GLP1RFOLH1NOD1GLO1EPOR
SCHEMBL23567477 0.94 GLP1R (0.61) GLP1RFOLH1NOD1
SCHEMBL24592948 0.94 GLP1R (0.61) GLP1RFOLH1NOD1
SCHEMBL23567479 0.94 GLP1R (0.61) GLP1RFOLH1NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022257979-A1 LONG-ACTING DUAL GIP/GLP-1 PEPTIDE CONJUGATES AND METHODS OF USE THE SCRIPPS RESEARCH INSTITUTE (US) 2022-12-15 — — WO disclosed
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