SCHEMBL27435532

SCHEMBL27435532

O=C(O)CCCCCCCCCCCCCCCCC(=O)NC(CCCCNC(=O)CCOCCOCCNC(=O)CCOCCOCCNC(=O)[C@H](CCCNC(=O)CBr)NC(=O)CBr)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.65
▸ FOLH1 Q04609 7/20 0.47
▸ NOD1 Q9Y239 1/20 0.41
▸ GLO1 Q04760 1/20 0.40
▸ EPOR P19235 1/20 0.39
▸ FNTA P49354 1/20 0.39
▸ FNTB P49356 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24712871 1.00 GLP1R (0.65) GLP1RFOLH1NOD1GLO1EPOR
SCHEMBL23489667 1.00 GLP1R (0.65) GLP1RFOLH1NOD1GLO1EPOR
SCHEMBL18202847 1.00 GLP1R (0.65) GLP1RFOLH1NOD1GLO1EPOR
SCHEMBL23475917 1.00 GLP1R (0.65) GLP1RFOLH1NOD1GLO1EPOR
SCHEMBL23475915 1.00 GLP1R (0.65) GLP1RFOLH1NOD1GLO1EPOR
SCHEMBL23475960 1.00 GLP1R (0.65) GLP1RFOLH1NOD1GLO1EPOR
SCHEMBL24711913 1.00 GLP1R (0.65) GLP1RFOLH1NOD1GLO1EPOR
SCHEMBL23567477 0.94 GLP1R (0.61) GLP1RFOLH1NOD1
SCHEMBL24592948 0.94 GLP1R (0.61) GLP1RFOLH1NOD1
SCHEMBL23567479 0.94 GLP1R (0.61) GLP1RFOLH1NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207363-A1 MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF THE SCRIPPS RESEARCH INSTITUTE 2024-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207363-A1 MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF SGMS1, SGMS2, PHOSPHO1 GLP1R 372/4885FOLH1 10/4885NOD1 2918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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