Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21741224 | 0.81 | KDM4E (0.50) | ALDH1A1HTTSMN1; SMN2TDP1EGFR | |
| SCHEMBL17773342 | 0.79 | ALDH1A1 (0.42) | GAAALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL11269504 | 0.79 | ALDH1A1 (0.53) | GAAALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL17773341 | 0.77 | ALDH1A1 (0.40) | GAAALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL13719453 | 0.77 | GAA (0.50) | GAAALDH1A1HTTSMN1; SMN2EGFR | |
| SCHEMBL24331648 | 0.77 | ALDH1A1 (0.50) | GAAALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL2038297 | 0.76 | GAA (0.41) | GAAALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL29641984 | 0.75 | GAA (0.48) | GAAALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL20314964 | 0.74 | GAA (0.44) | GAAALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL17777792 | 0.74 | ALDH1A1 (0.46) | GAAALDH1A1HTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022232195-A2 | COVALENT APTAMERS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-11-03 | — | — | WO | disclosed |