Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24713778 | 1.00 | USP2 (0.36) | USP2CYP11B1CYP11B2CYP3A4CYP2D6 | |
| SCHEMBL15451904 | 1.00 | USP2 (0.36) | USP2CYP11B1CYP11B2CYP3A4CYP2D6 | |
| SCHEMBL25049534 | 0.88 | USP2 (0.45) | USP2CYP3A4CYP2D6CYP1A2TSHR | |
| SCHEMBL15962732 | 0.88 | USP2 (0.45) | USP2CYP3A4CYP2D6CYP1A2TSHR | |
| SCHEMBL14154564 | 0.88 | USP2 (0.41) | USP2CYP3A4CYP2D6CYP1A2TSHR | |
| SCHEMBL14207975 | 0.86 | USP2 (0.38) | USP2CYP3A4CYP2D6CYP1A2TSHR | |
| SCHEMBL357309 | 0.86 | CYP11B1 (0.37) | CYP11B1CYP11B2CYP1A2TSHR | |
| SCHEMBL23508665 | 0.86 | USP2 (0.40) | USP2CYP2D6CYP1A2TSHR | |
| SCHEMBL17859514 | 0.84 | USP2 (0.33) | USP2CYP2D6CYP1A2 | |
| SCHEMBL12955231 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3661941-B1 | THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2022-12-14 | — | — | EP | disclosed |