Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15962732 | 1.00 | USP2 (0.45) | USP2CYP1A2TSHRCYP2D6CYP2C9 | |
| SCHEMBL23508665 | 0.94 | USP2 (0.40) | USP2CYP1A2TSHRCYP2D6CYP2C9 | |
| SCHEMBL15962738 | 0.92 | USP2 (0.45) | USP2CYP1A2TSHRCYP2D6CYP2C9 | |
| SCHEMBL15451904 | 0.88 | USP2 (0.36) | USP2CYP1A2TSHRCYP2D6CYP3A4 | |
| SCHEMBL23509081 | 0.88 | USP2 (0.36) | USP2TSHRCYP2D6CYP2C9HSD17B10 | |
| SCHEMBL12946061 | 0.88 | USP2 (0.47) | USP2CYP1A2TSHRCYP2D6CYP2C9 | |
| SCHEMBL24713161 | 0.88 | USP2 (0.36) | USP2CYP1A2TSHRCYP2D6CYP3A4 | |
| SCHEMBL24713778 | 0.88 | USP2 (0.36) | USP2CYP1A2TSHRCYP2D6CYP3A4 | |
| SCHEMBL22449729 | 0.86 | USP2 (0.39) | USP2CYP1A2TSHRCYP2D6CYP2C9 | |
| SCHEMBL14148838 | 0.85 | USP2 (0.49) | USP2CYP1A2TSHRCYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018810-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2023-02-16 | — | — | WO | disclosed |