Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | FAP | Q12884 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29558815 | 0.85 | DPP4 (0.67) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL214373 | 0.85 | DPP4 (0.67) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL13472178 | 0.83 | DPP4 (0.51) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL13637939 | 0.82 | DPP4 (0.55) | DPP4DPP8DPP9DPP7ACE | |
| Sitagliptin SCHEMBL3513247 | 0.77 | DPP4 (0.86) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL25840245 | 0.76 | DPP4 (0.57) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3793968 | 0.74 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3793975 | 0.74 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL28452793 | 0.74 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL4535123 | 0.73 | DPP4 (0.59) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257686-A1 | TRANSAMINASE, IMMOBILIZED TRANSAMINASE AND USE FOR PREPARING SITAGLIPTIN | 弈柯莱生物科技(上海)股份有限公司 | 2022-12-15 | — | — | WO | disclosed |