Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30127848 | 0.89 | ADORA1 (0.43) | GHSRMAPTMEN1KMT2ARXFP1 | |
| SCHEMBL22027659 | 0.89 | ADORA1 (0.43) | GHSRMAPTMEN1KMT2ARXFP1 | |
| SCHEMBL24713476 | 0.85 | ADORA2A (0.40) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL24713307 | 0.80 | MAPT (0.37) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL24713254 | 0.77 | ADORA1 (0.44) | LMNAMEN1KMT2ARXFP1NPC1 | |
| SCHEMBL20702503 | 0.76 | ADORA2A (0.48) | MAPTLMNAADORA2ANPSR1GFER | |
| SCHEMBL29607036 | 0.75 | CSNK2A2 (0.49) | MEN1KMT2ARXFP1NPC1RAB9A | |
| SCHEMBL24349424 | 0.75 | CSNK2A2 (0.49) | MEN1KMT2ARXFP1NPC1RAB9A | |
| SCHEMBL20702421 | 0.75 | ADORA1 (0.47) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL20702388 | 0.74 | CSNK2A1 (0.46) | MEN1KMT2AALDH1A1RXFP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3661941-B1 | THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2022-12-14 | — | — | EP | disclosed |