Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | POLQ | O75417 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22063313 | 0.83 | ALDH1A1 (0.55) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL22063902 | 0.82 | PIK3CG (0.40) | MAPTKMT2AMEN1ALDH1A1ALOX5 | |
| SCHEMBL30128074 | 0.82 | ALDH1A1 (0.56) | MAPTKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL29607036 | 0.81 | CSNK2A2 (0.49) | KMT2AMEN1RAB9AKDRNPC1 | |
| SCHEMBL24349424 | 0.81 | CSNK2A2 (0.49) | KMT2AMEN1RAB9AKDRNPC1 | |
| SCHEMBL24713254 | 0.81 | ADORA1 (0.44) | KMT2AMEN1LMNARAB9AKDR | |
| SCHEMBL24713738 | 0.81 | ADORA2A (0.35) | POLQPIK3CGADORA1PIK3CDPIK3CA | |
| SCHEMBL30128039 | 0.80 | PIK3CD (0.41) | MAPTKMT2AMEN1ALDH1A1ALOX5 | |
| SCHEMBL24713290 | 0.80 | GHSR (0.35) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL22064038 | 0.80 | POLQ (0.36) | MAPTKMT2AALDH1A1ALOX5POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3661941-B1 | THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2022-12-14 | — | — | EP | disclosed |