Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14478703 | 0.84 | SQOR (0.49) | SQORMAPTCASP1KMT2APDCD1 | |
| SCHEMBL13144468 | 0.78 | SQOR (0.57) | SQORMAPTCASP1KMT2APDCD1 | |
| SCHEMBL30439186 | 0.76 | MAPT (0.56) | SQORMAPTCASP1KMT2AMEN1 | |
| SCHEMBL20764961 | 0.76 | MAPT (0.56) | SQORMAPTCASP1KMT2AMEN1 | |
| SCHEMBL17703511 | 0.76 | SQOR (0.51) | SQORMAPTCASP1KMT2AALDH1A1 | |
| SCHEMBL6916456 | 0.75 | ALOX5AP (0.51) | SQORMAPTCASP1KMT2ARECQL | |
| SCHEMBL9756304 | 0.74 | MAPT (0.45) | SQORMAPTCASP1KMT2AMEN1 | |
| SCHEMBL3767625 | 0.73 | QPCT (0.54) | SQORMAPTCASP1KMT2AMEN1 | |
| SCHEMBL30505741 | 0.72 | SQOR (0.59) | SQORMAPTCASP1KMT2AMEN1 | |
| SCHEMBL29131667 | 0.72 | SQOR (0.59) | SQORMAPTCASP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3661941-B1 | THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2022-12-14 | — | — | EP | disclosed |