Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 14/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PDE2A | O00408 | 2/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.49 |
| ▸ | MTOR | P42345 | 2/20 | 0.49 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.49 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.49 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24713820 | 0.87 | PRKDC (0.54) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL29826538 | 0.87 | PRKDC (0.54) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL24713563 | 0.87 | PIK3CB (0.60) | PIK3CAPIK3CDPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL24713938 | 0.84 | PIK3CA (0.53) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL29826867 | 0.84 | PIK3CA (0.53) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL24713583 | 0.82 | PIK3CB (0.40) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL29826076 | 0.82 | PIK3CB (0.40) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL1638958 | 0.82 | PIK3CA (0.53) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL12666453 | 0.82 | PRKDC (0.52) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL24713629 | 0.82 | PRKDC (0.51) | PRKDCPIK3CAPIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022164812-A1 | PHOSPHOINOSITIDE 3 KINASE BETA INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | GEODE THERAPEUTICS INC. (US) | 2022-08-04 | — | — | WO | disclosed |