Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29826476 | 0.92 | KDM4E (0.35) | TNKSKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL24714348 | 0.92 | KDM4E (0.35) | TNKSKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL12666555 | 0.91 | KDM4E (0.35) | TNKSKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL30768042 | 0.90 | KDM4E (0.34) | TNKSKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL1639065 | 0.83 | PIK3CB (0.52) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL1637326 | 0.83 | CSNK2A2 (0.37) | TNKSKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL24713822 | 0.82 | KDM4E (0.35) | TNKSKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL1866751 | 0.73 | PIK3CB (0.41) | KDM4EALDH1A1HSD17B10TSHRPIK3CD | |
| SCHEMBL30193094 | 0.73 | PIK3CA (0.61) | PIK3CAPIK3CB | |
| SCHEMBL23887051 | 0.73 | PIK3CA (0.39) | CCNE2CDK1CDK4CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022164812-A1 | PHOSPHOINOSITIDE 3 KINASE BETA INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | GEODE THERAPEUTICS INC. (US) | 2022-08-04 | — | — | WO | disclosed |