Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 13/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.41 |
| ▸ | FBP1 | P09467 | 4/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812445 | 0.88 | ENPP1 (0.58) | ENPP1EGFRERBB2FBP1ERBB4 | |
| SCHEMBL217338 | 0.86 | PDE10A (0.52) | ENPP1EGFR | |
| SCHEMBL3239272 | 0.85 | ENPP1 (0.68) | ENPP1EGFRERBB2FBP1PDGFRB | |
| Hydrochloric Acid SCHEMBL28016254 | 0.84 | PDE10A (0.51) | ENPP1EGFRPDGFRB | |
| SCHEMBL5230842 | 0.83 | KDR (0.43) | ENPP1EGFRERBB2 | |
| SCHEMBL7225895 | 0.83 | EGFR (0.49) | EGFRPDGFRB | |
| SCHEMBL5227290 | 0.81 | KDR (0.44) | ENPP1EGFRERBB2 | |
| SCHEMBL27136671 | 0.79 | ENPP1 (0.48) | ENPP1EGFRERBB2FBP1ERBB4 | |
| SCHEMBL5231086 | 0.78 | EPHA2 (0.43) | EGFRERBB2 | |
| SCHEMBL7225093 | 0.78 | RET (0.50) | ERBB2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693505-A | Heteroaryl derivative compounds and uses thereof | 沃若诺伊公司 | 2024-03-12 | — | — | CN | disclosed |
| EP-4328222-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | Voronoi Inc. (KR) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |