Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.58 |
| ▸ | EGFR | P00533 | 12/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.48 |
| ▸ | FBP1 | P09467 | 6/20 | 0.47 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27136671 | 0.90 | ENPP1 (0.48) | ENPP1EGFRERBB2FBP1ERBB4 | |
| SCHEMBL24714036 | 0.88 | ENPP1 (0.48) | ENPP1EGFRERBB2FBP1ERBB4 | |
| SCHEMBL29834779 | 0.87 | ENPP1 (0.46) | ENPP1EGFRERBB2FBP1ERBB4 | |
| SCHEMBL2476964 | 0.81 | RET (0.55) | ENPP1EGFR | |
| SCHEMBL471137 | 0.81 | KDM1A (0.57) | EGFR | |
| SCHEMBL27150849 | 0.81 | ENPP1 (0.41) | ENPP1EGFRERBB2 | |
| SCHEMBL22076878 | 0.81 | FBP1 (0.55) | ENPP1EGFRFBP1 | |
| SCHEMBL13969805 | 0.80 | ENPP1 (0.59) | ENPP1EGFRERBB2FBP1ERBB4 | |
| SCHEMBL1013257 | 0.79 | ENPP1 (0.88) | ENPP1EGFRERBB2FBP1ERBB4 | |
| SCHEMBL13091000 | 0.79 | ENPP1 (0.58) | ENPP1EGFRERBB2FBP1ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0782570-A1 | SUBSTITUTED HETEROAROMATIC COMPOUNDS AND THEIR USE IN MEDICINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996009294-A1 | SUBSTITUTED HETEROAROMATIC COMPOUNDS AND THEIR USE IN MEDICINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-03-28 | — | — | WO | disclosed |