Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.50 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.50 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 11/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 3/20 | 0.43 |
| ▸ | KRAS | P01116 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24714692 | 0.94 | KDR (0.47) | KDRERBB2EPHA2EPHB4EGFR | |
| SCHEMBL24714641 | 0.89 | EGFR (0.56) | KDREGFRSRCMAPK1 | |
| SCHEMBL24714943 | 0.88 | EGFR (0.56) | KDREGFRSRCMAPK1 | |
| SCHEMBL24714929 | 0.85 | EGFR (0.54) | KDREGFRMAPK1 | |
| SCHEMBL24713875 | 0.84 | EGFR (0.55) | KDREGFRMAPK1 | |
| SCHEMBL24714715 | 0.83 | EGFR (0.53) | KDREGFRSRCMAPK1 | |
| SCHEMBL30032472 | 0.81 | EGFR (0.65) | ERBB2EPHB4EGFR | |
| SCHEMBL30031569 | 0.81 | EGFR (0.61) | ERBB2EGFR | |
| SCHEMBL24714051 | 0.81 | EGFR (0.65) | ERBB2EPHB4EGFR | |
| SCHEMBL27148255 | 0.81 | EGFR (0.61) | ERBB2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |