Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 7/20 | 0.48 |
| ▸ | KDR | P35968 | 6/20 | 0.48 |
| ▸ | FLT1 | P17948 | 2/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KIF5B | P33176 | 2/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | LCK | P06239 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24714943 | 0.98 | EGFR (0.56) | EGFRMAPK1RETKDRFLT1 | |
| SCHEMBL24714929 | 0.96 | EGFR (0.54) | EGFRMAPK1RETKDRFLT1 | |
| SCHEMBL24713875 | 0.94 | EGFR (0.55) | EGFRMAPK1RETKDRFLT1 | |
| SCHEMBL24714715 | 0.93 | EGFR (0.53) | EGFRMAPK1RETKDRFLT1 | |
| SCHEMBL24714050 | 0.89 | KDR (0.50) | EGFRMAPK1KDRSRC | |
| SCHEMBL24715171 | 0.86 | EGFR (0.61) | EGFRRETKDRFLT1FGFR1 | |
| SCHEMBL24713876 | 0.85 | EGFR (0.56) | EGFRMAPK1RETKDRFLT1 | |
| SCHEMBL24713874 | 0.85 | KDR (0.52) | EGFRMAPK1RETKDRFLT1 | |
| SCHEMBL24714014 | 0.83 | RET (0.55) | EGFRRETKDRKIF5B | |
| SCHEMBL29168733 | 0.83 | EGFR (0.54) | EGFRMAPK1RETKDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |