Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.66 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.66 |
| ▸ | DUS2 | Q9NX74 | 1/20 | 0.66 |
| ▸ | KDR | P35968 | 17/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.56 |
| ▸ | FLT1 | P17948 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24714969 | 0.91 | EGFR (0.63) | EGFRERBB3DUS2KDRFGFR1 | |
| SCHEMBL30031460 | 0.82 | EGFR (0.63) | EGFRSRC | |
| SCHEMBL27137968 | 0.81 | EGFR (0.72) | EGFR | |
| SCHEMBL30979939 | 0.81 | EGFR (0.72) | EGFR | |
| SCHEMBL24713933 | 0.80 | EGFR (0.51) | EGFRERBB3DUS2KDR | |
| SCHEMBL25247597 | 0.79 | EGFR (0.64) | EGFRERBB3DUS2KDR | |
| SCHEMBL21801932 | 0.79 | EGFR (1.00) | EGFRERBB3DUS2KDRSRC | |
| SCHEMBL29617536 | 0.79 | EGFR (1.00) | EGFRERBB3DUS2KDRSRC | |
| SCHEMBL29478966 | 0.79 | EGFR (1.00) | EGFRERBB3DUS2KDRSRC | |
| SCHEMBL27139767 | 0.79 | EGFR (0.52) | EGFRERBB3DUS2KDRFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |