Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 6/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.50 |
| ▸ | KDR | P35968 | 4/20 | 0.49 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 9/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27152211 | 0.88 | EGFR (0.62) | EPHA2ERBB2EPHB4EGFR | |
| SCHEMBL30820508 | 0.88 | EGFR (0.62) | EPHA2ERBB2EPHB4EGFR | |
| SCHEMBL27136650 | 0.86 | EGFR (0.56) | EPHA2ERBB2KDREPHB4EGFR | |
| SCHEMBL30822092 | 0.86 | EGFR (0.56) | EPHA2ERBB2KDREPHB4EGFR | |
| SCHEMBL27145372 | 0.82 | EGFR (0.57) | EPHA2ERBB2KDREGFRPIK3CD | |
| SCHEMBL27148662 | 0.81 | EPHA2 (0.57) | EPHA2ERBB2EGFR | |
| SCHEMBL30032119 | 0.81 | EPHA2 (0.57) | EPHA2ERBB2EGFR | |
| SCHEMBL30820474 | 0.81 | EPHA2 (0.57) | EPHA2ERBB2EGFR | |
| SCHEMBL27145045 | 0.80 | EGFR (0.57) | EPHA2KDREGFRPIK3CDPIK3CA | |
| SCHEMBL1614506 | 0.78 | KDR (0.75) | EPHA2ERBB2KDREPHB4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |